Alert: 8 Types of Drugs Linked to Increased Dementia Risk

found these drugs were associated with a 15% increased risk of dementia and 21% increased risk of Alzheimer’s disease, especially with long-term use.

What to do:

Short-term use is generally lower risk. If used long-term, ask your doctor about tapering or alternatives like cognitive behavioral therapy (CBT).

💊 2. Anticholinergic Drugs (High Concern)

Used for: Overactive bladder, allergies, depression, Parkinson’s, COPD

What research suggests:

Risk increases with duration of use:

1–89 days: +10% risk

1–3 years: +49% risk

3+ years: +66%

risk

Common examples:

Oxybutynin

Diphenhydramine (Benadryl)

Amitriptyline, nortriptyline

Hydroxyzine

Cyclobenzaprine

What to do:

Request a medication review. Many safer alternatives